According to Wikipedia:
The farcical plot focuses on Eddie Kettle, a very short young man newly married to Georgina, who is extremely tall. They board a Hudson River Day Line boat headed for the Honeymoon Inn in Poughkeepsie. Also on board are extremely tall athlete Percy Darling and his very short bride Elsie. Chaos ensues when the couples cross paths and accidentally trade partners. The vaudeville-style adventure continues at the hotel, where guests with names like Gay Anne Giddy, Fullern A. Goat, Tayleurs Dummee, Always Innit, and Madame Matroppo, a sex-crazed opera coach whose student is "Lily Pond" (Lily Pons), pop in and out of rooms while an inebriated desk clerk tries to sort through all the madness. Eventually the mismatched newlyweds find their way back to each other and, not surprisingly, true love prevails.